Dosage form and Strength of Halaven (Eribulin Mesylate) Injection: It is a sterile solution for injection.
It is a clear, colorless, sterile solution in a single-dose vial.
Each 2ml vial contains Eribulin Mesylate 1mg equivalent to Eribulin 0.88mg.
Mechanism Of Action of Halaven (Eribulin Mesylate) Injection: It inhibits the growth phase of microtubules without affecting the shortening phase and sequesters tubulin into nonproductive aggregates. Eribulin exerts its effects via a tubulin-based antimitotic mechanism leading to G2/M cell-cycle block, disruption of mitotic spindles, and, ultimately, apoptotic cell death after prolonged mitotic blockage.
In addition, eribulin treatment of human breast cancer cells caused changes in morphology and gene expression as well as decreased migration and invasiveness in vitro.
Administration of Halaven (Eribulin Mesylate) Injection: It should be administered intravenously over 2 to 5 minutes on Day 1 and 8 of every 21-day cycle.
Do not self-medicate the therapy.
Use it under a medical supervision only.
Therapeutic Use of Halaven (Eribulin Mesylate) Injection: It is used to treat the symptoms of Metastatic Breast Cancer and Liposarcoma.
It is used to treat adults with Breast cancer that has spread to other parts of the body.
Usage Instruction of Halaven (Eribulin Mesylate) Injection: For Intravenous Use only.
Single use vial.
Discard unused portion.
Do not self-medicate the therapy.
Use it under a medical supervision only.
Side Effects: Neutropenia,
Peripheral neuropathy,
Anemia,
Hair Loss,
Dizziness,
Swelling of your face, lips, tongue, or throat,
Uneven heart rate,
Fatigue,
Decreased Weight,
Dizziness,
Hypotension.
Safety Precautions:
Alcohol:
The study of the drug in alcoholic patient is not known.
However, it is advisable to consult a doctor for personalized advice.
Pregnancy:
It is unsafe to use in pregnant women.
It can harm your unborn baby.
Pregnant women should consult their doctor for alternative treatment options.
Lactating Mothers:
The study of the drug in Lactating mother is not known.
It is not exactly known whether the drug may pass into the milk.
However, it is advisable to not breastfeed while using this medication.
Lactating mothers should seek medical advice for appropriate alternatives.
Driving:
It is unsafe to drive after taking the medication as it may cause dizziness and decrease alertness.
Consult your doctor for guidance on driving safety.
Renal Impairment:
It should be used with precaution in Renally Impaired patients.
However, it is important to consult a doctor for proper evaluation and potential dosage adjustments.
Hepatic Impairment:
It should be used with precaution in Hepatically Impaired patients.
Consulting a doctor is crucial for appropriate guidance.
Contraindications: Known hypersensitivity.
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